Description

2-(Chloroformyl)-3-Phenylpropenoic Acid Methyl Ester is a versatile and reactive chemical intermediate, primarily valued for its bifunctional nature, containing both an acid chloride and an ester group. This compound is crucial for the synthesis of complex molecules, enabling the construction of heterocyclic compounds and advanced pharmaceutical scaffolds. It is an essential raw material for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific functional groups into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex aromatic or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its reactivity to create novel bioactive molecules.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers where specific phenylpropenoate derivatives are required.
• Research & Development: Employed in academic and industrial R&D labs for method development and the creation of novel chemical entities for screening.
• Peptide Mimetics & Conjugates: Its reactive chloroformyl group makes it suitable for coupling reactions in the development of peptide analogs and bioconjugates.

Basic Information

Product Name	2-(Chloroformyl)-3-Phenylpropenoic Acid Methyl Ester
CAS No.	32046-42-7
Molecular Formula	C11H9ClO3
Molecular Weight	224.64 g/mol
Synonyms	Methyl 2-(Chloroformyl)-3-phenylpropenoate; 3-Phenyl-2-(chlorocarbonyl)acrylic Acid Methyl Ester; 2-(Chlorocarbonyl)-3-phenylacrylic Acid Methyl Ester; Methyl 3-Phenyl-2-(chloroformyl)acrylate; (E)-Methyl 3-phenyl-2-(chloroformyl)acrylate; Propenoic acid, 2-(chloroformyl)-3-phenyl-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 2-(Chloroformyl)-3-Phenylpropenoic Acid Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.