Description

(+)-5,5',7,7'-Tetramethoxy-2,2'-Bis(4-Methoxyphenyl)-[8,8'-Bi(4H-1-Benzopyran)]-4,4'-Dione is a high-purity, optically active biflavonoid derivative characterized by its complex, symmetrical molecular architecture. This compound matters as a critical advanced intermediate or reference standard in research and development, where precise stereochemistry and structural integrity are paramount. It is primarily needed by pharmaceutical R&D laboratories and specialty chemical manufacturers engaged in developing novel therapeutic agents, particularly in areas like enzyme inhibition or as a scaffold for complex molecular synthesis.

Application

• Pharmaceutical Research Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates targeting specific biological pathways.
• Biochemical Reference Standard: Used for analytical method development, calibration, and quality control in laboratories studying flavonoid-based compounds.
• Enzyme Inhibition Studies: Investigated for potential activity as an inhibitor for specific enzymes due to its biflavonoid structure.
• Organic Synthesis Scaffold: Utilized in advanced organic chemistry to construct more complex, polyfunctional molecules for material science or medicinal chemistry.
• Academic & Institutional Research: Employed in universities and research institutes for studies on natural product derivatives, photochemistry, or asymmetric synthesis.

Basic Information

Product Name	(+)-5,5',7,7'-Tetramethoxy-2,2'-Bis(4-Methoxyphenyl)-[8,8'-Bi(4H-1-Benzopyran)]-4,4'-Dione
CAS No.	31771-75-2
Molecular Formula	C44H38O12
Molecular Weight	758.77 g/mol
Synonyms	(+)-Amentoflavone Tetramethyl Ether; (2R,3R)-2,3-Dihydro-5,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one dimer; Tetramethoxy Amentoflavone; NSC 122180; 4H,4'H-1,1'-Bibenzo[g]chromene-4,4'-dione derivative; (+)-5,5',7,7'-Tetramethoxy-2,2'-bis(4-methoxyphenyl)-8,8'-bichromone; 8,8'-Biapoamentoflavone tetramethyl ether
EINECS	Contact for details

Quality Control

Our (+)-5,5',7,7'-Tetramethoxy-2,2'-Bis(4-Methoxyphenyl)-[8,8'-Bi(4H-1-Benzopyran)]-4,4'-Dione is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as chiral purity, assay, and related substances are provided and available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Chiral Purity ([α]D)	Contact for details
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.