Description

Nafronyl CAS NO 31329-57-4 is a pharmaceutical active ingredient and a vasodilator compound. It is a critical intermediate in the synthesis of medications used to treat peripheral vascular disorders and cerebral circulatory issues. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for conditions like intermittent claudication and cognitive impairment.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key component in the formulation of vasodilator drugs.
• Peripheral Vasodilator Formulations: Used in medications for treating peripheral arterial diseases, such as intermittent claudication.
• Cerebral Vasodilator Formulations: Incorporated into drugs aimed at improving cerebral blood flow for conditions like vascular dementia or cognitive deficits.
• Chemical Intermediate: Serves as a crucial building block in the multi-step synthesis of more complex pharmaceutical molecules.
• Research & Development: Utilized in preclinical and clinical studies for investigating new therapeutic applications for vascular disorders.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Nafronyl
CAS No.	31329-57-4
Molecular Formula	C24H33NO4
Molecular Weight	399.53 g/mol
Synonyms	Nafronyl Oxalate; Nafronyl Acid Oxalate; 2-(Diethylamino)ethyl 3-methyl-2-phenyl-1-naphthoate oxalate; Nafridrofuryl Oxalate; LS-121; EU-1806; Praxilene (brand name); Nafronyl Acid Oxalate Salt
EINECS	250-558-6

Quality Control

Our Nafronyl is manufactured under cGMP conditions, ensuring the highest standards of purity and consistency for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent pharmacopeial requirements. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.