Description

(3Aβ,6Aβ,9Aβ,9Bα)-3β,9β-Dimethyl-4β-Hydroxy-6-Methylenedodecahydroazuleno[4,5-B]Furan-2,8-Dione is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity and structural complexity. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its unique molecular scaffold.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Biochemical Research: Investigated for its potential biological activities as a sesquiterpene lactone analog.
• Reference Standard: Used as an analytical standard for quality control and method development in analytical laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and specialty chemicals.

Basic Information

Product Name	(3Aβ,6Aβ,9Aβ,9Bα)-3β,9β-Dimethyl-4β-Hydroxy-6-Methylenedodecahydroazuleno[4,5-B]Furan-2,8-Dione
CAS No.	30825-69-5
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	6-Methylenedodecahydroazuleno[4,5-b]furan-2,8-dione, 3,9-dimethyl-4-hydroxy-, (3aβ,4β,6aβ,9aβ,9bα)-; 3,9-Dimethyl-4-hydroxy-6-methylenedodecahydroazuleno[4,5-b]furan-2,8-dione; Alantolactone isomer; Isoalantolactone (related compound); Helenin derivative; Sesquiterpene lactone derivative; Decahydroazulene derivative; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our (3Aβ,6Aβ,9Aβ,9Bα)-3β,9β-Dimethyl-4β-Hydroxy-6-Methylenedodecahydroazuleno[4,5-B]Furan-2,8-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades and analytical data packages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% (High Purity Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.