Description

Colfenamate is a non-steroidal anti-inflammatory drug (NSAID) compound, specifically a fenamate derivative, with the CAS registry number 30531-86-3. It serves as a key pharmaceutical intermediate and a potent cyclooxygenase (COX) inhibitor, valued for its anti-inflammatory and analgesic properties. This compound is essential for researchers and manufacturers in the pharmaceutical industry developing new therapeutic agents and for use in biochemical studies investigating inflammatory pathways.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of advanced anti-inflammatory drug candidates and prodrugs.
• Biochemical Research: Used as a reference standard and tool compound in studies of prostaglandin synthesis and COX enzyme inhibition.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method development in analytical laboratories.
• Preclinical Development: Employed in pharmacological and toxicological studies during early-stage drug discovery.

Basic Information

Product Name	Colfenamate
CAS No.	30531-86-3
Molecular Formula	C16H14ClNO2
Molecular Weight	287.74 g/mol
Synonyms	2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid; Diclofenac impurity C; 1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one; Colfenamic acid; NSC 339539; Fenamate derivative; COX-2 inhibitor intermediate
EINECS	Contact for details

Quality Control

Our Colfenamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent control of residual solvents and heavy metals. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to ensure traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.