Description

Cyclobutanecarbonyl Chloride, 3-Chloro- (8Ci,9Ci) is a highly reactive and versatile chemical intermediate, specifically a functionalized acyl chloride derivative. Its value lies in its ability to introduce the cyclobutane moiety and an acid chloride functional group into target molecules, enabling efficient synthesis of complex structures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those containing strained ring systems like cyclobutanes, which are explored for their unique biological activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclobutane ring can contribute to improved efficacy and environmental profile.
• Organic Synthesis Reagent: Serves as a crucial reagent for peptide coupling, esterification, and amidation reactions in complex multi-step synthetic routes.
• Material Science Research: Employed in the development of specialty polymers and advanced materials that require specific, rigid molecular architectures.
• Chemical Biology Probes: Utilized to create labeled compounds or affinity probes for studying biological mechanisms and target identification.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 3-Chloro- (8Ci,9Ci)
CAS No.	30494-32-7
Molecular Formula	C5H6Cl2O
Molecular Weight	152.99 g/mol
Synonyms	3-Chlorocyclobutanecarbonyl chloride; 3-Chlorocyclobutane-1-carbonyl chloride; 1-(Chlorocarbonyl)-3-chlorocyclobutane; Cyclobutanecarbonyl chloride, 3-chloro-; 3-Chloro-cyclobutanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Chloride, 3-Chloro- (8Ci,9Ci) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.