Description

Grayanotoxin III 6,14-Diacetate is a specific acetylated derivative of the naturally occurring neurotoxin grayanotoxin III. This compound is of significant interest in biochemical and pharmacological research due to its role as a key intermediate and probe for studying sodium channel modulation. It is primarily sought by research institutions and pharmaceutical development companies engaged in neurobiological studies, natural product chemistry, and the investigation of novel analgesic or cardiotonic agents.

Application

• Neuroscience Research: Used as a precise biochemical tool to study voltage-gated sodium (Na+) channel function and modulation in neuronal cells.
• Pharmacological Probe Development: Serves as a critical intermediate in the synthesis and structure-activity relationship (SAR) studies of grayanotoxin analogs for potential therapeutic applications.
• Natural Product Chemistry: Employed as a reference standard for the identification, quantification, and isolation of grayanotoxin derivatives from plant sources like Rhododendron species.
• Toxicology Studies: Utilized in controlled laboratory settings to understand the mechanism of action and toxicological profile of grayanotoxin-related compounds.
• Academic & Institutional Research: Supports fundamental research in plant biochemistry, electrophysiology, and medicinal chemistry.

Basic Information

Product Name	Grayanotoxin III 6,14-Diacetate
CAS No.	30460-34-5
Molecular Formula	C24H36O8
Molecular Weight	452.54 g/mol
Synonyms	Grayanotoxin III Diacetate; 6,14-Diacetoxygrayanotoxin III; 3,5-Dihydroxy-14-(2-hydroxyethyl)-4,4,9,13-tetramethyl-8-oxapentacyclo[11.2.1.0¹,¹⁰.0²,⁶.0⁹,¹³]hexadecane-5,14-diyl diacetate; Andromedotoxin derivative; Acetylandromedol; Rhodotoxin derivative
EINECS	Contact for details

Quality Control

Our Grayanotoxin III 6,14-Diacetate is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to rigorous analytical standards, utilizing techniques such as HPLC, NMR, and MS for characterization, ensuring the material meets the exacting requirements of advanced scientific research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.