Description

(1Ar)-9Aα-Acetyloxy-1Aα,1Bβ,4,4A,5,7Aα,7B,8,9,9A-Decahydro-4Aβ,7Bα,9β-Trihydroxy-1,1,6,8α-Tetramethyl-5-Oxo-1H-Cyclopropa[3,4]Benz[1,2-E]Azulene-3-Carbaldehyde is a complex, high-purity diterpenoid derivative with a unique cyclopropaazulene core structure. This compound serves as a critical advanced intermediate for the synthesis of novel bioactive molecules in pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel anti-inflammatory, antiviral, or anticancer drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex, polyfunctional scaffold.
• Process Chemistry Development: Serves as a starting material or intermediate in the development and scale-up of new synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Potential intermediate for developing new plant growth regulators or pesticides with novel modes of action.
• Fine Chemical Synthesis: Used in the production of high-value, complex fragrance or flavor ingredients.
• Academic Research: Valuable compound for studies in organic synthesis methodology, natural product chemistry, and chemical biology.

Basic Information

Product Name	(1Ar)-9Aα-Acetyloxy-1Aα,1Bβ,4,4A,5,7Aα,7B,8,9,9A-Decahydro-4Aβ,7Bα,9β-Trihydroxy-1,1,6,8α-Tetramethyl-5-Oxo-1H-Cyclopropa[3,4]Benz[1,2-E]Azulene-3-Carbaldehyde
CAS No.	30358-72-6
Molecular Formula	C25H34O7
Molecular Weight	446.53 g/mol
Synonyms	9-Deoxy-9α-acetoxy-8-epi-triptonide; 8-Epi-9-deoxy-9α-acetoxytriptonide; 9α-Acetoxy-8-epi-9-deoxytriptonide; (1aR,4aS,7aS,7bS,8R,9R,9aR)-9-(Acetyloxy)-1a,4a,7a,7b,8,9,9a,9b-octahydro-4a,7b,9-trihydroxy-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulene-3-carbaldehyde; Triptonide derivative; Tripdiolide acetate derivative; Celastrol precursor.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep the container tightly sealed when not in use to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.