Description

Grayanotoxin Iv is a potent diterpenoid neurotoxin belonging to the grayanane family, identified by CAS No. 30272-17-4. This high-purity reference standard is critical for research and development in neuropharmacology and toxicology, offering reliable and consistent quality for precise analytical work. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and analytical service providers focusing on ion channel modulation, natural product chemistry, and safety assessment.

Application

• Pharmacological Research: Used as a reference standard in studies of voltage-gated sodium (Na+) channel modulation and neuronal excitability.
• Toxicology & Safety Assessment: Serves as a key analytical standard for the detection and quantification of grayanotoxins in food safety, forensic analysis, and clinical toxicology.
• Natural Product Chemistry: Employed in the isolation, characterization, and synthesis studies of complex diterpenoid structures.
• Biochemical Assay Development: Utilized as a precise tool in developing high-throughput screening assays for neuroactive compounds.
• Academic Reference Material: Provides a certified standard for university and institutional research into plant-derived toxins and their mechanisms of action.
• Quality Control in Herbal Products: Acts as a marker compound for the QC/QA of botanical extracts and traditional medicines derived from Ericaceae family plants (e.g., rhododendron, azalea).

Basic Information

Product Name	Grayanotoxin Iv
CAS No.	30272-17-4
Molecular Formula	C22H36O7
Molecular Weight	412.52 g/mol
Synonyms	Grayanotoxin IV; Grayanotoxin 4; Acetylandromedol; Andromedotoxin Acetate; Rhodojaponin VI; 3β,6β,14β-Triacetoxy-5β,10β-dihydroxy-1(15),2-grayanotoxadiene; 1(15),2-Grayanotoxadiene-3β,5β,6β,10β,14β-pentol 3,6,14-triacetate
EINECS	Contact for details

Quality Control

Our Grayanotoxin Iv is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.