Description

1-Palmitoyl-Sn-Glycero-3-Phospho-Sn-1-Glycerol Sodium Salt is a high-purity, synthetic phospholipid derivative, specifically a sodium salt of a phosphatidylglycerol. This compound is a critical building block in advanced lipid-based formulations, offering precise structural control for research and development. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries who require defined lipid components for creating liposomes, lipid nanoparticles (LNPs), and other sophisticated delivery systems.

Application

• Lipid Nanoparticle (LNP) Formulation: A key excipient for the development of mRNA and other nucleic acid delivery systems, contributing to the stability and cellular uptake of therapeutic cargo.
• Liposome & Vesicle Preparation: Used as a component in the lipid bilayer to modulate surface charge, stability, and fusion properties for drug delivery and diagnostic applications.
• Biomimetic Membrane Research: Serves as a model phospholipid in biophysical studies to investigate membrane dynamics, protein-lipid interactions, and cellular processes.
• Pulmonary Surfactant Research: Investigated as a synthetic component in studies related to lung surfactant function and replacement therapies.
• Advanced Cosmetic Actives: Incorporated into high-performance skincare formulations such as nanosomes and other encapsulation systems for targeted and sustained release of active ingredients.
• Bioconjugation & Labeling: Provides a reactive phospholipid backbone for the attachment of targeting ligands, dyes, or other functional molecules in diagnostic and therapeutic probes.

Basic Information

Item	Detail
Product Name	1-Palmitoyl-Sn-Glycero-3-Phospho-Sn-1-Glycerol Sodium Salt
CAS No.	30227-18-0
Molecular Formula	C22H42NaO10P
Molecular Weight	520.52 g/mol
Synonyms	1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-sn-glycerol) Sodium Salt; PG(16:0/0:0) Sodium Salt; L-α-Phosphatidylglycerol (16:0) Sodium Salt; 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1'-sn-glycerol) Sodium Salt; Sodium 1-palmitoyl-sn-glycero-3-phosphoglycerol; PG(16:0) Sodium Salt; 1-Palmitoyl Phosphatidylglycerol Sodium Salt; Synthetic Phosphatidylglycerol Sodium Salt
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-Sn-Glycero-3-Phospho-Sn-1-Glycerol Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and water uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform/methanol mixtures
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.