Description

(R)-Bromosuccinic Acid CAS NO 3972-41-6 is a high-value chiral building block, an enantiomerically pure derivative of succinic acid. This compound is essential for the synthesis of optically active pharmaceuticals and advanced materials, where stereochemical control is critical. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing drugs for metabolic and neurological disorders.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides and pesticides to enhance efficacy and reduce environmental impact.
• Asymmetric Catalyst Ligand: Serves as a precursor for ligands in metal-catalyzed asymmetric reactions, crucial for creating single-enantiomer compounds.
• Biochemical Research: Employed in proteomics and enzyme studies as a modifier or a standard for chiral analysis.
• Polymer Modification: Acts as a functional monomer for introducing bromine and carboxylic acid groups into specialty polymers.
• Peptide Synthesis: Used to incorporate chiral, functionalized residues into synthetic peptides.

Basic Information

Product Name	(R)-Bromosuccinic Acid
CAS No.	3972-41-6
Molecular Formula	C4H5BrO4
Molecular Weight	197.00 g/mol
Synonyms	(R)-2-Bromobutanedioic Acid; (2R)-2-Bromosuccinic Acid; D-(-)-Bromosuccinic Acid; (R)-(-)-Bromosuccinic Acid; Bromosuccinic Acid, (R)-; (R)-Bromobutanedioic Acid; L-Bromosuccinic Acid (obsolete); Succinic Acid, 2-bromo-, (2R)-
EINECS	223-607-8

Quality Control

Our (R)-Bromosuccinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	158 - 165 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.