Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-(n-Methyl)-Ethanolamine is a high-purity synthetic phospholipid derivative, specifically a methylated phosphatidylethanolamine (PE). This compound is a critical building block in advanced lipid-based formulations, offering enhanced stability and specific functional properties. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing next-generation drug delivery systems and biomembrane models.

Application

• Liposome & Nanoparticle Formulation: A key component for creating stable, surface-modified liposomal carriers for targeted drug delivery, including mRNA vaccines and cancer therapeutics.
• Biomembrane Research: Used to synthesize model membranes and lipid bilayers for studying cell membrane dynamics, protein-lipid interactions, and permeability.
• Excipient Development: Serves as a functional excipient to modulate the surface charge, stability, and fusogenic properties of lipid-based pharmaceutical formulations.
• Diagnostic Reagents: Employed in the production of diagnostic kits and assays that utilize liposome technology for signal amplification.
• Cosmetic Actives Delivery: Incorporated into high-end cosmetic formulations for the encapsulation and controlled release of active ingredients.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-(n-Methyl)-Ethanolamine
CAS No.	3930-13-0
Molecular Formula	C38H76NO8P
Molecular Weight	706.0 g/mol
Synonyms	DPPE-Methyl; 1,2-Dipalmitoyl-sn-glycero-3-phospho(N-methylethanolamine); N-Methyl DPPE; Methyl-PE (16:0/16:0); Phosphatidyl-N-methylethanolamine (dipalmitoyl); 1,2-Dihexadecanoyl-sn-glycero-3-phospho-(N-methylethanolamine); (2R)-2,3-Bis(hexadecanoyloxy)propyl (2-(methylamino)ethyl) phosphate
EINECS	223-500-3

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-(n-Methyl)-Ethanolamine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.