Description

1,2-Dihexadecanoyl-Sn-Glycero-3-Phospho[Dimethylaminoethanol] is a high-purity synthetic phospholipid, specifically a phosphatidylcholine derivative with defined acyl chains. This compound is critical for creating stable, well-defined lipid bilayers and vesicles for advanced research and formulation development. It is an essential material for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise control over membrane properties and surface charge.

Application

• Liposome & Nanoparticle Formulation: A key structural component for creating unilamellar vesicles (LUVs, SUVs) and solid lipid nanoparticles (SLNs) for drug delivery systems.
• Membrane Biophysics Research: Used to construct model cell membranes (e.g., supported lipid bilayers, black lipid membranes) to study protein-lipid interactions, membrane permeability, and fusion mechanisms.
• Biomimetic Coatings & Surface Modification: Employed to create biocompatible, non-fouling surfaces on medical devices, sensors, and diagnostic platforms.
• Cell Culture & Transfection Reagents: Serves as a raw material in the production of lipid-based transfection reagents for introducing nucleic acids into cells.
• Reference Standard & Analytical Chemistry: Used as a certified reference material (CRM) for lipidomics studies, method development, and quality control in lipid analysis (HPLC, MS).
• Cosmetic Actives Delivery: Incorporated into nanocarrier systems for the targeted and sustained delivery of active ingredients in high-end cosmetic formulations.

Basic Information

Product Name	1,2-Dihexadecanoyl-Sn-Glycero-3-Phospho[Dimethylaminoethanol]
CAS No.	3922-61-0
Molecular Formula	C40H80NO8P
Molecular Weight	734.04 g/mol
Synonyms	DPPC (Dipalmitoylphosphatidylcholine); 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine; Dipalmitoylphosphatidylcholine; Dipalmitoyl PC; L-α-Phosphatidylcholine, dipalmitoyl; 1,2-Dipalmitoylphosphatidylcholine; 1,2-Dihexadecanoylphosphatidylcholine; PC(16:0/16:0)
EINECS	223-480-8

Quality Control

Our 1,2-Dihexadecanoyl-Sn-Glycero-3-Phospho[Dimethylaminoethanol] is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and assay, TLC for lipid profiling, and NMR for structural confirmation. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol; forms liposomes in aqueous buffers
Phase Transition Temp (Tm)	Approx. 41°C
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.