Description

2,6-Pyridinedicarboxylic Acid Chloride is a versatile and highly reactive organic intermediate, serving as a crucial building block for the synthesis of complex molecules. Its value lies in its dual acid chloride functionality, which readily undergoes reactions with nucleophiles like amines and alcohols to form amides and esters, enabling efficient derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for constructing pyridine-based ligands, active pharmaceutical ingredients (APIs), and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing a 2,6-disubstituted pyridine core for receptor targeting.
• Ligand Synthesis: Used to prepare sophisticated chelating ligands for catalysis and metal-organic frameworks (MOFs), leveraging the pyridine nitrogen for coordination chemistry.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing high-performance polyamides or polyesters with enhanced thermal and chemical stability.
• Agrochemical Development: Building block for creating novel herbicides, fungicides, and insecticides that incorporate the pyridine moiety for biological activity.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for the efficient preparation of diamides, diesters, and other functionalized pyridine derivatives.
• Material Science: Used in the development of advanced organic electronic materials, sensors, and liquid crystals due to its rigid, planar structure.

Basic Information

Product Name	2,6-Pyridinedicarboxylic Acid Chloride
CAS No.	3739-94-4
Molecular Formula	C7H3Cl2NO2
Molecular Weight	204.01 g/mol
Synonyms	2,6-Pyridinedicarbonyl Dichloride; 2,6-Dichlorocarbonylpyridine; Dipicolinoyl Chloride; Pyridine-2,6-dicarboxylic Acid Chloride; 2,6-Bis(chlorocarbonyl)pyridine; 2,6-Pyridinedicarboxylic Acid Dichloride; Dipicolinic Acid Dichloride; 3739-94-4
EINECS	223-124-8

Quality Control

Our 2,6-Pyridinedicarboxylic Acid Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.