Description

cis-4-Aminocyclohexanecarboxylic Acid CAS NO 3685-23-2 is a versatile chiral cyclohexane derivative featuring both an amino and a carboxylic acid functional group. This compound serves as a critical building block in organic synthesis, enabling the construction of complex molecules with precise stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Peptidomimetics & Conformationally Restricted Peptides: Used to introduce rigid, cyclohexane-based scaffolds into peptide backbones to enhance stability, bioavailability, and receptor selectivity.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Ligand & Catalyst Development: Precursor for chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Monomer or modifier for specialty polymers and dendrimers where the amino and acid groups facilitate polymerization or functionalization.
• Biochemical Research: Tool compound for studying enzyme inhibition, receptor binding, and as a standard in analytical method development.

Basic Information

Product Name	cis-4-Aminocyclohexanecarboxylic Acid
CAS No.	3685-23-2
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	cis-4-Aminocyclohexanecarboxylic Acid; (1r,4r)-4-Aminocyclohexanecarboxylic Acid; cis-4-Amino-1-cyclohexanecarboxylic Acid; 4-Aminocyclohexanecarboxylic Acid, cis-; 4-Aminocyclohexanecarboxylic Acid; 4-Aminohexahydrobenzoic Acid; 4-Aminocyclohexane-1-carboxylic Acid; 4-ACCA
EINECS	Contact for details

Quality Control

Our cis-4-Aminocyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% cis-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.