Description

(20S)-16α-Hydroxy-4,14-Dimethyl-3β-(Methylamino)-20-(Dimethylamino)-9β,19-Cyclo-5α-Pregnane-4β-Methanol is a complex, multi-functional steroidal alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate molecular architecture, featuring multiple chiral centers and functional groups, makes it a valuable key intermediate for developing novel bioactive compounds. This high-purity chemical is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized steroidal drugs and reference standards.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel steroidal pharmaceuticals and potential therapeutic agents.
• Biochemical Research: Used as a reference standard or precursor in studies investigating steroidal biosynthesis pathways, enzyme inhibition, and receptor binding activities.
• Fine Chemical Synthesis: Acts as a specialized starting material or intermediate for creating complex, high-value molecules in custom synthesis and process development.
• Academic Research: Employed in university and institutional laboratories for methodological development in organic chemistry and stereoselective synthesis.
• Process Chemistry: Utilized in scaling up synthetic routes for the production of target molecules in pilot plants and development-scale manufacturing.

Basic Information

Product Name	(20S)-16α-Hydroxy-4,14-Dimethyl-3β-(Methylamino)-20-(Dimethylamino)-9β,19-Cyclo-5α-Pregnane-4β-Methanol
CAS No.	3668-23-3
Molecular Formula	C₂₇H₄₈N₂O₂
Molecular Weight	432.69 g/mol
Synonyms	16α-Hydroxy-4,14-dimethyl-3β-(methylamino)-20-(dimethylamino)-9β,19-cyclo-5α-pregnan-4β-methanol; (20S)-16α-Hydroxy-4,14-dimethyl-3β-(methylamino)-20-(dimethylamino)-9β,19-cyclo-5α-pregnan-4β-methanol; 9β,19-Cyclo-5α-pregnane-4β-methanol, 16α-hydroxy-4,14-dimethyl-3β-(methylamino)-20-(dimethylamino)-, (20S)-; Conessine derivative; Wrightine derivative; Kurchi alkaloid intermediate; N-Methylconessine analog
EINECS	Contact for details

Quality Control

Our high-purity steroidal intermediate is manufactured under controlled conditions to ensure batch-to-batch consistency and reliability. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.