Description

2,3-Dihydro-1,4-Benzodioxine-2-Carbonyl Chloride is a versatile and highly reactive acid chloride derivative of the 1,4-benzodioxane scaffold. This compound serves as a critical pharmaceutical intermediate and synthetic building block for constructing complex molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the 1,4-benzodioxane moiety.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Used to create specialized ligands for metal catalysis and organocatalysts.
• Polymer Chemistry: Monomer or modifier for producing specialty polymers with specific thermal or chemical resistance properties.
• Material Science Research: Intermediate in the development of advanced organic materials, such as liquid crystals or organic semiconductors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	2,3-Dihydro-1,4-Benzodioxine-2-Carbonyl Chloride
CAS No.	3663-81-8
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	1,4-Benzodioxane-2-carbonyl chloride; 2,3-Dihydro-1,4-benzodioxin-2-carbonyl chloride; 1,4-Benzodioxan-2-carbonyl chloride; 2-Carboxy-2,3-dihydro-1,4-benzodioxine chloride; 2-Chlorocarbonyl-2,3-dihydro-1,4-benzodioxine; 2,3-Dihydrobenzo[b][1,4]dioxine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1,4-Benzodioxine-2-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.