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2-[Hydroxy-[2-Hydroxy-3-[(E)-Octadec-9-Enoyl]Oxy-Propoxy]Phosphoryl]Oxyethyl-Trimethyl-Azanium CAS NO 3542-29-8


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CAS No.:3542-29-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[Hydroxy-[2-Hydroxy-3-[(E)-Octadec-9-Enoyl]Oxy-Propoxy]Phosphoryl]Oxyethyl-Trimethyl-Azanium is a high-purity, synthetic phospholipid derivative, specifically a phosphocholine esterified with oleic acid. This compound is valued for its role as a key intermediate and functional material in advanced formulations requiring precise amphiphilic properties. It is primarily utilized by research institutions and industrial manufacturers in the life sciences and specialty chemical sectors for developing lipid-based delivery systems and biomimetic membranes.

Application

  • Lipid Nanoparticle (LNP) Formulation: A critical component in the synthesis of ionizable cationic lipids for mRNA and siRNA delivery systems.
  • Liposome & Niosome Production: Used as a functional phospholipid to create stable, uniform vesicles for drug encapsulation and targeted delivery.
  • Biomimetic Membrane Research: Serves as a building block for constructing model cell membranes to study protein-lipid interactions and membrane dynamics.
  • Cosmetic Actives Carrier: Employed in high-end cosmetic formulations to enhance the skin penetration and stability of active ingredients.
  • Diagnostic Reagent Development: Utilized in the preparation of reagents for clinical diagnostics and biochemical assays.
  • Surface Modification Agent: Applied to modify material surfaces to improve biocompatibility or introduce specific functional groups.

Basic Information

Product Name 2-[Hydroxy-[2-Hydroxy-3-[(E)-Octadec-9-Enoyl]Oxy-Propoxy]Phosphoryl]Oxyethyl-Trimethyl-Azanium
CAS No. 3542-29-8
Molecular Formula C₂₈H₅₆NO₈P
Molecular Weight 565.72 g/mol
Synonyms 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphocholine; Lyso-PC(18:1(9Z)); Lyso-oleoylphosphatidylcholine; 1-Monsoleoylphosphatidylcholine; LPC(18:1); (9Z)-1-[Hydroxy(2-{trimethylammonio}ethoxy)phosphinyl]oxy-3-(octadec-9-enoyloxy)propan-2-ol; 1-Oleoyl-2-lyso-sn-glycero-3-phosphocholine; Oleoyl lysophosphatidylcholine
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Quality Control

Our 2-[Hydroxy-[2-Hydroxy-3-[(E)-Octadec-9-Enoyl]Oxy-Propoxy]Phosphoryl]Oxyethyl-Trimethyl-Azanium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and advanced material synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white waxy solid or viscous liquid
Identification (HPLC/MS) Conforms to reference standard
Assay (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Water Content (KF) ≤ 3.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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