Description

Piperazine,1,4-Bis(4-Chlorophenyl)- is a specialized aromatic piperazine derivative characterized by its symmetrical structure with chlorophenyl substituents. This compound serves as a critical high-purity intermediate in advanced organic synthesis, where its rigid, halogenated framework is essential for constructing complex molecular architectures. It is primarily required by pharmaceutical R&D and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antimicrobial research.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating high-performance polymers and resins with specific thermal and chemical properties.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Piperazine,1,4-Bis(4-Chlorophenyl)-
CAS No.	3367-54-2
Molecular Formula	C16H16Cl2N2
Molecular Weight	307.22 g/mol
Synonyms	1,4-Bis(4-chlorophenyl)piperazine; N,N'-Bis(4-chlorophenyl)piperazine; 1,4-Di(4-chlorophenyl)piperazine; 4,4'-(Piperazine-1,4-diyl)dichlorobenzene; Bis(4-chlorophenyl)piperazine; 1,4-Bis(p-chlorophenyl)piperazine; 3367-54-2; 1,4-Bis(4-chlorophenyl)-piperazine
EINECS	222-155-8

Quality Control

Every batch of Piperazine,1,4-Bis(4-Chlorophenyl)- is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and compliance with your project specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.