Description

1,4-Di-o-Tolylpiperazine is a high-purity organic compound belonging to the piperazine class, serving as a versatile chemical intermediate. Its value lies in its role as a key building block for synthesizing more complex molecules, particularly in advanced pharmaceutical and agrochemical research. This product is essential for R&D chemists and process development scientists in the pharmaceutical, fine chemical, and material science industries seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targeted drugs and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific piperazine-based structures.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or chain extender in the production of specialty polymers, such as polyurethanes and polyamides, to impart specific thermal or mechanical properties.
• Research & Development: A valuable tool compound in academic and industrial laboratories for medicinal chemistry and chemical biology studies.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex organic dyes and colorants.

Basic Information

Product Name	1,4-Di-o-Tolylpiperazine
CAS No.	3367-47-3
Molecular Formula	C18H22N2
Molecular Weight	266.38 g/mol
Synonyms	1,4-Bis(2-methylphenyl)piperazine; 1,4-Di(2-tolyl)piperazine; 1,4-Di-o-tolyl-piperazine; N,N'-Di-o-tolylpiperazine; 1,4-Bis(o-tolyl)piperazine; Piperazine, 1,4-bis(2-methylphenyl)-; 1,4-Di(2-methylphenyl)piperazine; DTBP
EINECS	222-150-8

Quality Control

Our 1,4-Di-o-Tolylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.