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1,2-Dipentadecanoyl-Sn-Glycero-3-Phosphocholine CAS NO 3355-27-9


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CAS No.:3355-27-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dipentadecanoyl-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid belonging to the phosphatidylcholine class. This compound is a critical building block for creating advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precisely defined lipid components for consistent, reproducible results.

Application

  • Liposome & Nanoparticle Formulation: A key component in the synthesis of liposomes and lipid nanoparticles (LNPs) for drug and gene delivery, including mRNA vaccine formulations.
  • Biomembrane Research: Used to create model lipid bilayers and vesicles (e.g., giant unilamellar vesicles, GUVs) for studying membrane biophysics, protein-lipid interactions, and cellular processes.
  • Pharmaceutical Excipient: Serves as a functional excipient in solid and liquid dosage forms to enhance solubility and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
  • Diagnostic Reagents: Employed in the development of diagnostic assays and kits that utilize membrane-bound enzymes or receptors.
  • Cosmetic & Dermal Delivery: Incorporated into topical formulations and cosmetic products as an emulsifier and penetration enhancer for active ingredients.
  • Biomaterial Coatings: Used to create biocompatible, non-fouling coatings on medical devices and implants to improve hemocompatibility.

Basic Information

Product Name 1,2-Dipentadecanoyl-Sn-Glycero-3-Phosphocholine
CAS No. 3355-27-9
Molecular Formula C38H76NO8P
Molecular Weight 706.0 g/mol
Synonyms 1,2-Dipentadecanoylphosphatidylcholine; PC(15:0/15:0); DPPC (C15:0); 1,2-Di(pentadecanoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine(30:0); 3-sn-Phosphatidylcholine, 1,2-dipentadecanoyl-; 1,2-Diheptadecanoylphosphatidylcholine (common misnomer); L-α-Phosphatidylcholine, dipentadecanoyl-
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Quality Control

Our 1,2-Dipentadecanoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Solubility Soluble in chloroform, methanol, ethanol; forms dispersions in water
Loss on Drying ≤ 1.0%
Heavy Metals ≤ 10 ppm
Residual Solvents Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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