Description

1-Hydroxy-3-Methylcholanthrene is a polycyclic aromatic hydrocarbon derivative of significant interest in biochemical and toxicological research. This compound serves as a critical reference standard and metabolite in studies investigating the metabolic activation and carcinogenic mechanisms of polycyclic aromatic hydrocarbons. It is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories focused on environmental toxicology, cancer research, and drug metabolism.

Application

• Biochemical Research Standard: Used as a high-purity reference material for calibrating analytical instruments like HPLC and GC-MS in metabolite studies.
• Toxicology & Carcinogenicity Studies: Acts as a key intermediate or metabolite in research exploring the metabolic pathways and DNA-adduct formation of methylcholanthrene derivatives.
• Pharmaceutical R&D: Employed in investigative studies related to the metabolism of complex organic molecules and the development of analytical methods for metabolite detection.
• Environmental Analysis: Serves as a standard for monitoring and analyzing polycyclic aromatic hydrocarbon (PAH) metabolites in environmental and biological samples.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, biochemistry, and molecular toxicology.

Basic Information

Product Name	1-Hydroxy-3-Methylcholanthrene
CAS No.	3342-98-1
Molecular Formula	C21H16O
Molecular Weight	284.35 g/mol
Synonyms	3-Methylcholanthren-1-ol; 1-Hydroxy-3-methylcholanthrene; 3-MC-1-ol; 1-OH-3-MC; Hydroxymethylcholanthrene; 3-Methyl-1-hydroxycholanthrene; 1-Hydroxy-3-MCA
EINECS	Contact for details

Quality Control

Our 1-Hydroxy-3-Methylcholanthrene is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatography. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light tan powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.