Description

Aspergillomarasmine B is a potent, naturally occurring dipeptide metabolite produced by certain Aspergillus species. This compound is of significant interest in biochemical and pharmacological research due to its role as a specific and potent inhibitor of metallo-β-lactamase (MBL) enzymes. It is primarily utilized by research institutions and pharmaceutical development teams focused on combating antibiotic resistance, studying enzyme mechanisms, and developing novel therapeutic adjuvants.

Application

• Biochemical Research: Used as a specific probe to study the structure, function, and inhibition mechanisms of metallo-β-lactamase (MBL) enzymes.
• Antibiotic Resistance Research: Serves as a key compound in developing novel therapeutic strategies to restore the efficacy of β-lactam antibiotics against resistant bacterial strains.
• Pharmaceutical Development: Investigated as a potential adjuvant or co-drug to enhance the effectiveness of existing carbapenem and other β-lactam antibiotics.
• Microbiology Studies: Applied in research to understand bacterial resistance pathways and the role of MBLs in hospital-acquired infections.
• Enzyme Inhibitor Screening: Used as a reference standard in high-throughput screening assays for discovering new MBL inhibitors.
• Academic & Institutional Research: Essential for universities and research institutes conducting advanced studies in medicinal chemistry, enzymology, and infectious diseases.

Basic Information

Item	Details
Product Name	Aspergillomarasmine B
CAS No.	3262-58-6
Molecular Formula	C9H15N3O7
Molecular Weight	277.23 g/mol
Synonyms	L-Aspartyl-(3-amino-3-carboxypropyl)aziridine-2-carboxylic acid; Aspergillomarasmin B; AMB; (2S)-2-[[(2S,3S)-3-Amino-2-aziridinylcarbonyl]amino]-4-[[(1S)-1-carboxy-2-(carboxymethylamino)ethyl]amino]-4-oxobutanoic acid; L-β-(L-γ-Amino-α,γ-dicarboxybutyryl)-L-azetidine-2-carboxylic acid; Aspergillomarasmine
EINECS	Contact for details

Quality Control

Our Aspergillomarasmine B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable and reproducible results for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.