Description

(2R,5S)-1-Benzyl-2,5-Dimethyl-Piperazine is a high-purity, stereochemically defined chiral piperazine derivative. This compound serves as a critical chiral building block and ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control for novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Catalysis: Used as a precursor for chiral ligands and organocatalysts in metal-catalyzed and organocatalytic reactions to induce stereoselectivity.
• Agrochemical Research: Employed in developing chiral active ingredients for herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology & Proteomics: Serves as a scaffold for designing molecular probes and enzyme inhibitors to study biological pathways.
• Material Science: Potential monomer or additive for creating polymers with specific chiral or optical properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific stereochemistry at the 2 and 5 positions of the piperazine ring.

Basic Information

Product Name	(2R,5S)-1-Benzyl-2,5-Dimethyl-Piperazine
CAS No.	3138-88-3
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	(2R,5S)-1-Benzyl-2,5-dimethylpiperazine; 1-Benzyl-(2R,5S)-2,5-dimethylpiperazine; (2R,5S)-1-Benzyl-2,5-dimethyl-piperazine; 1-Benzyl-2,5-dimethylpiperazine (stereoisomer); Benzyl-2,5-dimethylpiperazine; (R,S)-1-Benzyl-2,5-dimethylpiperazine; (2R,5S)-2,5-Dimethyl-1-benzylpiperazine; Piperazine, 1-benzyl-2,5-dimethyl-, (2R,5S)-
EINECS	Contact for details

Quality Control

Our (2R,5S)-1-Benzyl-2,5-Dimethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.