Description

1,2-Dipalmitoyl-3-Phosphatidylethanolamine is a synthetic, high-purity phospholipid that serves as a critical building block for advanced lipid-based formulations. Its value lies in its role as a primary component for creating stable, functional liposomes and lipid nanoparticles, which are essential for targeted drug delivery and membrane research. This product is primarily needed by pharmaceutical R&D teams, academic researchers in biophysics, and manufacturers of diagnostic reagents and cosmetic delivery systems seeking reliable, well-characterized lipid excipients.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for constructing stable vesicles used in drug delivery systems, including mRNA vaccines and cancer therapeutics.
• Membrane Biophysics Research: Used to create model lipid bilayers for studying membrane protein interactions, fusion processes, and membrane permeability.
• Diagnostic Reagent Manufacturing: Employed in the production of liposomal assays and as a component in diagnostic kits that require controlled membrane surfaces.
• Cosmetic & Dermal Delivery Systems: Acts as an emulsifier and carrier in advanced cosmetic formulations for the sustained release of active ingredients.
• Biomimetic Coatings & Materials: Utilized to develop biocompatible coatings for medical devices and sensors that mimic natural cell membranes.
• Cell Culture & Transfection: A component in lipid mixtures used for cell transfection reagents to introduce nucleic acids into cells.

Basic Information

Product Name	1,2-Dipalmitoyl-3-Phosphatidylethanolamine
CAS No.	3026-45-7
Molecular Formula	C39H78NO8P
Molecular Weight	720.00 g/mol
Synonyms	DPPE; 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine; Dipalmitoylphosphatidylethanolamine; Phosphatidylethanolamine, dipalmitoyl; L-α-Phosphatidylethanolamine, dipalmitoyl; PE(16:0/16:0); (R)-2,3-Bis(palmitoyloxy)propyl (2-aminoethyl) phosphate
EINECS	221-182-0

Quality Control

Our 1,2-Dipalmitoyl-3-Phosphatidylethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	190°C - 200°C
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.