Description

Chloroacetyl Fluoride is a highly reactive acyl halide intermediate essential for introducing the chloroacetyl group into target molecules. Its unique bifunctional reactivity makes it a critical building block for synthesizing complex fluorinated and chlorinated compounds. This product is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for advanced synthesis and derivatization.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides that require chloroacetyl or fluorinated motifs.
• Fluorinated Polymer Precursor: Serves as a monomer or modifying agent in the creation of specialty polymers with enhanced chemical resistance.
• Organic Synthesis Building Block: Employed in peptide coupling reactions, Friedel-Crafts acylations, and the preparation of heterocyclic compounds.
• Liquid Crystal & Electronic Chemical Production: Used in the synthesis of fluorinated liquid crystals and electronic chemicals for display and semiconductor applications.
• Research & Development: A valuable tool for medicinal chemistry and material science research exploring new fluorinated molecular entities.

Basic Information

Product Name	Chloroacetyl Fluoride
CAS No.	359-14-8
Molecular Formula	C2H2ClFO
Molecular Weight	96.49 g/mol
Synonyms	Chloroacetyl fluoride; 2-Chloroacetyl fluoride; Monofluoro chloroacetate; Chloroacetic acid fluoride; Fluorochloromethanone; α-Chloroacetyl fluoride; Chloroacetyl fluoride (CAF); 2-Chloro-1-fluoroethanone
EINECS	Contact for details

Quality Control

Our Chloroacetyl Fluoride is manufactured under stringent process controls to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including GC, HPLC, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.