Description

Chlorodifluoroacetyl Fluoride is a highly reactive fluorinated organic intermediate. This compound is valued for its role as a key building block in the synthesis of complex fluorinated molecules, offering a versatile difluoromethylenation reagent. It is primarily sought by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced properties. Its high reactivity makes it a critical component in advanced fluorination chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including antiviral and anticancer agents.
• Agrochemical Synthesis: Used to manufacture advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Fluorinated Polymer Production: Serves as a monomer or modifier in the creation of specialty polymers with enhanced chemical resistance and thermal stability.
• Organic Synthesis Reagent: Employed as a versatile difluorocarbene or acyl fluoride equivalent in complex organic transformations and fine chemical production.
• Liquid Crystal & Electronic Materials: Used in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials.
• Refrigerant & Propellant Research: Investigated as a potential intermediate for next-generation, low-global-warming-potential (GWP) fluorocarbon compounds.

Basic Information

Item	Detail
Product Name	Chlorodifluoroacetyl Fluoride
CAS No.	354-27-8
Molecular Formula	C2ClF3O
Molecular Weight	132.47 g/mol
Synonyms	Chlorodifluoroacetyl fluoride; Difluorochloroacetyl fluoride; Chlorodifluoroacetic acid fluoride; 2-Chloro-2,2-difluoroacetyl fluoride; Carbonochloridoyl difluoride; CF2ClC(O)F; Chlorodifluoroethanoyl fluoride
EINECS	206-558-5

Quality Control

Our Chlorodifluoroacetyl Fluoride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support our partners with full traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent moisture ingress and decomposition. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Acidity (Titration)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.