Description

L-Cycloserine is a cyclic amino acid derivative and a potent antibiotic with a unique mechanism of action. This compound is valued for its role as a competitive antagonist of D-alanine, inhibiting bacterial cell wall synthesis. It is primarily utilized in the pharmaceutical and life science research sectors. Key applications include its use as a reference standard and active pharmaceutical ingredient in antimicrobial research and development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex antimicrobial agents and therapeutic compounds.
• Microbiological Research: Used as a selective agent in culture media to study bacterial resistance mechanisms and cell wall biosynthesis pathways.
• Reference Standard: Employed in analytical laboratories for quality control, method validation, and identification via techniques like HPLC and mass spectrometry.
• Biochemical Studies: Acts as a tool compound to investigate enzyme inhibition, particularly targeting alanine racemase and D-alanyl-D-alanine ligase.
• Veterinary Medicine: Investigated for potential applications in treating bacterial infections in animals.

Basic Information

Item	Detail
Product Name	L-Cycloserine
CAS No.	339-72-0
Molecular Formula	C3H6N2O2
Molecular Weight	102.09 g/mol
Synonyms	(S)-4-Amino-3-isoxazolidinone; (S)-Cycloserine; D-4-Amino-3-isoxazolidinone (enantiomer); (-)-Cycloserine; L-4-Amino-3-isoxazolidinone; Antibiotic 106-7; Oxamycin; Seromycin; Orientomycin; Cycloserine L-form
EINECS	206-428-3

Quality Control

Our L-Cycloserine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency, meeting the requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA), including results for assay, related substances, and residual solvents, is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Microbial Enumeration	Meets standard bioburden limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.