Description

1,2,4-Triazolo[4,3-A]Pyrazine, 5,6,7,8-Tetrahydro-7-Nitroso-3-(Trifluoromethyl)- is a high-value, nitrogen-rich heterocyclic compound featuring a nitroso functional group and a trifluoromethyl substituent. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Medicinal Chemistry Building Block: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Material Science Precursor: Potential use in the synthesis of nitrogen-doped carbon materials, ligands for catalysis, and specialty polymers.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition and protein-ligand interactions due to its distinctive heterocyclic core.

Basic Information

Product Name	1,2,4-Triazolo[4,3-A]Pyrazine, 5,6,7,8-Tetrahydro-7-Nitroso-3-(Trifluoromethyl)-
CAS No.	2892260-32-9
Molecular Formula	C6H4F3N5O
Molecular Weight	219.13 g/mol
Synonyms	5,6,7,8-Tetrahydro-7-nitroso-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine; 7-Nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine; 3-(Trifluoromethyl)-7-nitroso-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine; [1,2,4]Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-7-nitroso-3-(trifluoromethyl)-; Nitroso-trifluoromethyl-triazolopyrazine intermediate; TFMP-Nitroso intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under low-light conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.