Description

Methanone, [4-[Bis(4-Chlorophenyl)Methyl]-1-Piperazinyl](2-Ethynyl-4-Thiazolyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly due to the presence of key functional groups like the ethynyl and piperazinyl moieties. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study specific biological pathways and protein interactions.
• Fine Chemical Synthesis: Acts as a specialized precursor for the custom synthesis of complex, high-value organic molecules for research purposes.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions conducting cutting-edge drug discovery programs.

Basic Information

Product Name	Methanone, [4-[Bis(4-Chlorophenyl)Methyl]-1-Piperazinyl](2-Ethynyl-4-Thiazolyl)-
CAS No.	2786829-70-5
Molecular Formula	C29H23Cl2N3OS
Molecular Weight	524.48 g/mol
Synonyms	(2-Ethynyl-4-thiazolyl)[4-[bis(4-chlorophenyl)methyl]-1-piperazinyl]methanone; 1-[(4-Chlorophenyl)(4-chlorophenyl)methyl]-4-(2-ethynyl-1,3-thiazole-4-carbonyl)piperazine; 4-[Bis(4-chlorophenyl)methyl]-1-(2-ethynyl-1,3-thiazole-4-carbonyl)piperazine; [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(2-ethynyl-4-thiazolyl)methanone
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.