Description

2(1H)-Quinoxalinone, 8-Fluoro-7-(Hydroxymethyl)-3-Methyl- is a high-purity, functionalized quinoxalinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides due to its bioactive quinoxaline core.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and material science.
• Fluorescent Probe Development: The fluorinated quinoxalinone structure is utilized in designing sensitive probes for biochemical assays and diagnostic imaging.
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors and light-emitting materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	2(1H)-Quinoxalinone, 8-Fluoro-7-(Hydroxymethyl)-3-Methyl-
CAS No.	2756334-27-5
Molecular Formula	C10H9FN2O2
Molecular Weight	208.19 g/mol
Synonyms	8-Fluoro-7-(hydroxymethyl)-3-methylquinoxalin-2(1H)-one; 3-Methyl-8-fluoro-7-(hydroxymethyl)-1,2-dihydroquinoxalin-2-one; 8-Fluoro-7-(hydroxymethyl)-3-methyl-1,2-dihydroquinoxalin-2-one; 8-Fluoro-7-(hydroxymethyl)-3-methyl-2(1H)-quinoxalinone; Fluoromethyl-methyl-quinoxalinone derivative; FHQ derivative; CAS 2756334-27-5
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinoxalinone, 8-Fluoro-7-(Hydroxymethyl)-3-Methyl- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO 9001 compliance standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.