Description

m-Peg9-Phosphonic Acid Ethyl Ester is a specialized, high-purity functionalized PEG derivative featuring a phosphonic acid ethyl ester group at the terminus of a methoxy-terminated nonaethylene glycol chain. This molecular architecture provides a unique combination of water solubility, metal-chelating capability, and a reactive site for further conjugation, making it a critical intermediate for advanced material synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and nanotechnology sectors for developing targeted drug delivery systems, surface-modifying nanoparticles, and creating novel polymeric materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing prodrugs and bioconjugates, enhancing drug solubility and targeting.
• Surface Functionalization Agent: Used to modify the surface of nanoparticles (e.g., gold, iron oxide) and quantum dots to improve biocompatibility and stability in aqueous media.
• Metal Chelation & Sequestration: The phosphonic acid ester group acts as an effective ligand for chelating metal ions, useful in catalysis and water treatment formulations.
• Polymer Chemistry: Employed as a monomer or functional chain-transfer agent in the synthesis of amphiphilic block copolymers and smart hydrogels.
• Diagnostic Reagent Synthesis: A precursor for creating contrast agents and fluorescent probes used in medical imaging and diagnostic assays.
• Lubricant & Additive Component: Incorporated into specialty lubricants and coatings to provide anti-wear and corrosion inhibition properties.

Basic Information

Product Name	m-Peg9-Phosphonic Acid Ethyl Ester
CAS No.	2699881-07-5
Molecular Formula	C21H45O13P
Molecular Weight	536.55 g/mol
Synonyms	mPEG9-phosphonic acid ethyl ester; 2-[2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl ethylphosphonate; Ethyl 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylphosphonate; Methoxy-PEG9-phosphonic acid ethyl ester; mPEG9-P(O)(OEt)OH; Poly(ethylene glycol) methyl ether phosphonic acid ethyl ester (n=9); 9-MEO-3,6,9,12,15,18,21,24,27-NONAOXA-30-AZA-33-PHOSPHAHENTRIACONTAN-1-OL, 33-OXO-
EINECS	Contact for details

Quality Control

Our m-Peg9-Phosphonic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing specific batch results are available upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place, ideally at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.