Description

(+/-)-Erythro-5,6-Dihydroxy-9(Z),12(Z)-Octadecadienoic Acid is a dihydroxy derivative of linoleic acid, a key intermediate in the biosynthesis of specialized pro-resolving mediators (SPMs) and other oxylipins. This compound matters for researchers and developers in the life sciences as it serves as a crucial building block for studying lipid metabolism, inflammation pathways, and for the synthesis of bioactive lipid analogs. Industries that need this high-purity biochemical include pharmaceutical R&D, biotechnology, and academic research institutions focused on metabolic and inflammatory disease models.

Application

• Biochemical Research: Used as a standard or intermediate in studies of lipoxygenase and cytochrome P450 pathways for the biosynthesis of oxylipins and eicosanoids.
• Pharmaceutical Development: Serves as a key precursor in the synthesis of novel pro-resolving mediators and other lipid-based therapeutic candidates targeting inflammation.
• Metabolic Pathway Analysis: Employed in in vitro and cellular assays to investigate the metabolism of polyunsaturated fatty acids and the role of specific hydroxy fatty acids.
• Reference Standard: Utilized as a high-purity analytical standard for the identification and quantification of related metabolites in complex biological samples via LC-MS or GC-MS.
• Enzymology Studies: Acts as a substrate for enzymes like epoxide hydrolases or as a product for specific hydroxylases, facilitating enzyme characterization and inhibitor screening.

Basic Information

Product Name	(+/-)-Erythro-5,6-Dihydroxy-9(Z),12(Z)-Octadecadienoic Acid
CAS No.	2692622-63-0
Molecular Formula	C18H32O4
Molecular Weight	312.44 g/mol
Synonyms	5,6-DiHODE; erythro-5,6-Dihydroxyoctadeca-9Z,12Z-dienoic acid; (±)-erythro-5,6-DiHODE; 5,6-Dihydroxy-9Z,12Z-octadecadienoic acid; Linoleic acid, 5,6-dihydroxy-; 9Z,12Z-5,6-DiHODE; 5,6-DHODE; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (+/-)-Erythro-5,6-Dihydroxy-9(Z),12(Z)-Octadecadienoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent exposure to atmospheric moisture. For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.