Description

Piperazine, 1-Ethyl-2-Methyl-, Hydrochloride (1:2), (2S)- is a high-purity, chiral piperazine derivative salt, specifically the dihydrochloride salt of the (2S)-enantiomer. This compound is a critical pharmaceutical intermediate and building block for the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical control. It is essential for manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality chiral synthons for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel APIs, especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in custom synthesis and the manufacture of specialty chemicals requiring a defined piperazine scaffold.
• Research & Development: A valuable compound for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name	Piperazine, 1-Ethyl-2-Methyl-, Hydrochloride (1:2), (2S)-
CAS No.	2664977-66-4
Molecular Formula	C7H18N2 • 2HCl
Molecular Weight	227.15 g/mol (for free base C7H18N2)
Synonyms	(2S)-1-Ethyl-2-methylpiperazine Dihydrochloride; (S)-1-Ethyl-2-methylpiperazine Dihydrochloride; 1-Ethyl-2-methylpiperazine Hydrochloride (2:1), (S)-; (S)-N-Ethyl-2-methylpiperazine Dihydrochloride; 1-Ethyl-2-methyl-(S)-piperazine Dihydrochloride; (2S)-1-Ethyl-2-methylpiperazine • 2HCl; (S)-EMPD • 2HCl; Chiral 1-Ethyl-2-methylpiperazine Salt
EINECS	Contact for details

Quality Control

Our Piperazine, 1-Ethyl-2-Methyl-, Hydrochloride (1:2), (2S)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with cGMP, ICH Q7, and REACH guidelines for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.