Description

(E)-3-(3,4-Dichlorophenyl)-n-(2-(4-(Methylsulfonyl)Piperazin-1-Yl)-2-Oxoethyl)Acrylamide is a high-purity, synthetic organic compound designed for advanced research and development applications. This molecule is of significant interest as a key pharmaceutical intermediate or biological probe due to its complex structure featuring dichlorophenyl, acrylamide, and methylsulfonyl piperazine moieties. It is primarily utilized by organizations in the pharmaceutical, biotechnology, and academic research sectors focused on drug discovery and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold for structure-activity relationship (SAR) studies in academic and industrial R&D labs.
• Kinase Inhibitor Development: The structural motifs suggest potential application in the design and synthesis of kinase inhibitors for oncology and inflammatory diseases.
• Biochemical Probe: Employed in biological assays to investigate protein-ligand interactions and elucidate specific cellular mechanisms.
• Custom Synthesis Starting Material: Provides a versatile, high-purity starting point for contract research organizations (CROs) and CDMOs performing custom chemical synthesis.

Basic Information

Product Name	(E)-3-(3,4-Dichlorophenyl)-n-(2-(4-(Methylsulfonyl)Piperazin-1-Yl)-2-Oxoethyl)Acrylamide
CAS No.	2505001-62-5
Molecular Formula	C16H18Cl2N3O4S
Molecular Weight	419.30 g/mol
Synonyms	(E)-3-(3,4-Dichlorophenyl)-N-[2-[4-(methylsulfonyl)piperazin-1-yl]-2-oxoethyl]prop-2-enamide; N-[(E)-3-(3,4-Dichlorophenyl)prop-2-enoyl]-N'-(methylsulfonyl)piperazine-1-acetamide; (E)-3-(3,4-Dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide; CAS 2505001-62-5; Acrylamide derivative with dichlorophenyl and methylsulfonyl piperazine
EINECS	Contact for details

Quality Control

Our (E)-3-(3,4-Dichlorophenyl)-n-(2-(4-(Methylsulfonyl)Piperazin-1-Yl)-2-Oxoethyl)Acrylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.