Description

tert-Butyl (S)-4-Benzyl-2-(2-Hydroxyethyl)Piperazine-1-Carboxylate Hydrochloride is a high-purity, chiral piperazine derivative and a key pharmaceutical intermediate. This compound is of significant value for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Chiral Synthesis: Utilized in asymmetric synthesis to introduce the (S)-configured piperazine moiety into complex molecular architectures.
• API Development: Serves as a precursor in the research and scale-up production of Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and bespoke intermediates.
• Process Chemistry: Employed in route scouting and the development of efficient, scalable manufacturing processes for new chemical entities.

Basic Information

Product Name	tert-Butyl (S)-4-Benzyl-2-(2-Hydroxyethyl)Piperazine-1-Carboxylate Hydrochloride
CAS No.	2453297-16-8
Molecular Formula	C18H29ClN2O3
Molecular Weight	356.89 g/mol
Synonyms	(S)-1-tert-Butyl 4-Benzyl 2-(2-Hydroxyethyl)piperazine-1,4-dicarboxylate Hydrochloride; (S)-tert-Butyl 4-benzyl-2-(2-hydroxyethyl)piperazine-1-carboxylate hydrochloride; 1-Boc-4-Benzyl-(S)-2-(2-Hydroxyethyl)piperazine Hydrochloride; (S)-1-Boc-4-Cbz-2-(2-Hydroxyethyl)piperazine HCl; (S)-N-Boc-4-Benzyl-2-(2-Hydroxyethyl)piperazine Hydrochloride; (S)-4-Benzyl-2-(2-hydroxyethyl)piperazine-1-carboxylic acid tert-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our tert-Butyl (S)-4-Benzyl-2-(2-Hydroxyethyl)Piperazine-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with stringent specifications for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.