Description

(3S,5S)-Piperidine-3,5-Diol Hydrochloride is a high-purity chiral piperidine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its defined stereochemistry and functionalized core make it an invaluable intermediate for constructing complex molecules with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Utilized as a scaffold or precursor in catalytic asymmetric reactions to introduce stereocenters.
• Medicinal Chemistry Research: Serves as a core structure for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probes: Used in the development of molecular probes to study enzyme mechanisms or biological pathways.
• Ligand and Catalyst Development: Potential precursor for chiral ligands or organocatalysts used in enantioselective transformations.

Basic Information

Product Name	(3S,5S)-Piperidine-3,5-Diol Hydrochloride
CAS No.	2445749-90-4
Molecular Formula	C5H11NO2 • HCl
Molecular Weight	153.61 g/mol (Free base: 117.15 g/mol)
Synonyms	(3S,5S)-3,5-Dihydroxypiperidine Hydrochloride; (3S,5S)-3,5-Piperidinediol Hydrochloride; (3S,5S)-Piperidine-3,5-diol HCl; (3S,5S)-3,5-Dihydroxy-piperidine hydrochloride; (3S,5S)-3,5-Dihydroxypiperidine HCl salt; (3S,5S)-3,5-Piperidinediol HCl salt; (3S,5S)-3,5-Dihydroxypiperidinium chloride
EINECS	Contact for details

Quality Control

Our (3S,5S)-Piperidine-3,5-Diol Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.