Description

1H-Purine-2,6-Dione, 8-Bromo-1,7-Di-2-Butyn-1-Yl-3,7-Dihydro-3-Methyl- is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated purine-dione structure. This compound is critical for enabling targeted molecular modifications in drug discovery and development programs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel purine-based drug candidates, including kinase inhibitors and antiviral agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate purine metabolism pathways.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies for optimizing the potency and selectivity of lead compounds.
• Organic Synthesis: Serves as a versatile precursor for further functionalization via its reactive bromo and alkyne groups.
• Academic Research: Employed in universities and R&D labs for developing new synthetic methodologies and exploring chemical biology.

Basic Information

Product Name	1H-Purine-2,6-Dione, 8-Bromo-1,7-Di-2-Butyn-1-Yl-3,7-Dihydro-3-Methyl-
CAS No.	2436762-89-7
Molecular Formula	C15H13BrN4O2
Molecular Weight	361.20 g/mol
Synonyms	8-Bromo-1,7-di(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-Bromo-1,7-dibut-2-ynyl-3-methylxanthine; 8-Bromo-1,7-di(2-butynyl)-3-methylxanthine; 8-Bromo-3-methyl-1,7-di(2-butyn-1-yl)xanthine; 8-Bromo-PD 116,948 analog; Brominated xanthine derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1H-Purine-2,6-Dione, 8-Bromo-1,7-Di-2-Butyn-1-Yl-3,7-Dihydro-3-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.