Description

3-(4-Chlorophenyl)Piperazine-2,5-Dione is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant synthetic interest. Its core value lies in its piperazinedione scaffold, which serves as a privileged structure for developing novel bioactive compounds, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the synthesis of new drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules for drug discovery programs targeting CNS disorders, oncology, and infectious diseases.
• Medicinal Chemistry Building Block: Used to construct piperazine- and diketopiperazine-based libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a synthetic intermediate in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes to study enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Institutional Research: Employed in university and government labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-(4-Chlorophenyl)Piperazine-2,5-Dione
CAS No.	2411634-61-0
Molecular Formula	C10H9ClN2O2
Molecular Weight	224.64 g/mol
Synonyms	3-(4-Chlorophenyl)-2,5-piperazinedione; 3-(p-Chlorophenyl)piperazine-2,5-dione; 1,4-Diazacyclohexane-2,5-dione, 3-(4-chlorophenyl)-; 3-(4-Chlorophenyl)-1,4-diazacyclohexane-2,5-dione; 4-Chlorophenyl Diketopiperazine Derivative; (4-Chlorophenyl)DKP Intermediate; CAS 2411634-61-0
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)Piperazine-2,5-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.