Description

(S)-tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate is a high-purity chiral piperazine derivative, serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with potential biological activity. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly for the synthesis of novel drug candidates targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) drugs and other bioactive molecules.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve drug-like properties.
• Process Chemistry Development: Serves as a starting material or intermediate in the development of scalable, cost-effective synthetic routes for potential new drugs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial batches for clinical trials.
• Academic Research: Utilized in university and institutional labs for studying synthetic methodologies and developing new catalytic asymmetric reactions.

Basic Information

Product Name	(S)-tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate
CAS No.	2411591-34-7
Molecular Formula	C15H20N2O3
Molecular Weight	276.33 g/mol
Synonyms	(S)-1-Boc-3-oxo-2-phenylpiperazine; (S)-1-(tert-Butoxycarbonyl)-3-oxo-2-phenylpiperazine; (S)-tert-Butyl 3-oxo-2-phenyl-1-piperazinecarboxylate; (S)-2-Phenyl-3-oxopiperazine-1-carboxylic acid tert-butyl ester; (S)-Boc-3-oxo-2-phenylpiperazine; 1-Piperazinecarboxylic acid, 3-oxo-2-phenyl-, 1,1-dimethylethyl ester, (2S)-; (S)-N-Boc-3-oxo-2-phenylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-Oxo-2-Phenylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.