Description

(2R,4R)-(2-Methyl-Piperidin-4-Yl)-Carbamic Acid Benzyl Ester is a high-purity, chiral piperidine derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a stereochemically defined scaffold essential for constructing complex molecules with precise biological activity. Pharmaceutical R&D and fine chemical manufacturers need it for developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Utilized as a stereocontrolling agent or a chiral auxiliary in catalytic and stoichiometric asymmetric reactions.
• Medicinal Chemistry: Serves as a core structural motif for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetics & Bioisosteres: Incorporated into peptide backbones to enhance metabolic stability, bioavailability, and receptor selectivity.
• Ligand & Catalyst Development: Used in the preparation of novel chiral ligands for transition metal catalysis.
• Academic & Industrial Research: Employed in chemical biology and methodological studies exploring new synthetic pathways.

Basic Information

Product Name	(2R,4R)-(2-Methyl-Piperidin-4-Yl)-Carbamic Acid Benzyl Ester
CAS No.	2409589-97-3
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	Benzyl (2R,4R)-2-methyl-4-piperidinylcarbamate; (2R,4R)-2-Methylpiperidine-4-carbamic Acid Benzyl Ester; (2R,4R)-N-(Benzyloxycarbonyl)-2-methyl-4-aminopiperidine; (2R,4R)-2-Methyl-4-(benzyloxycarbonylamino)piperidine; (2R,4R)-Cbz-2-Methyl-4-aminopiperidine; (2R,4R)-2-Methyl-4-N-Cbz-piperidine; (2R,4R)-2-Methyl-4-(N-Cbz)piperidine; (2R,4R)-2-Methyl-4-piperidyl carbamate benzyl ester
EINECS	Contact for details

Quality Control

Our (2R,4R)-(2-Methyl-Piperidin-4-Yl)-Carbamic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.