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Bocnh-Peg11-Ch2Ch2N3 CAS NO 2395004-21-2


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CAS No.:2395004-21-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bocnh-Peg11-Ch2Ch2N3 (CAS NO 2395004-21-2) is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring a Boc-protected amine at one terminus and an azide group at the other. This compound is essential for creating stable, water-soluble conjugates in advanced bioconjugation and materials science applications. It is specifically designed for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise and reliable cross-linking agents for drug delivery systems, surface functionalization, and the synthesis of complex biomaterials.

Application

  • Bioconjugation and ADC Development: Used as a key linker for attaching cytotoxic drugs to antibodies or proteins in Antibody-Drug Conjugate (ADC) research and production.
  • PEGylation: Serves as a functionalized PEG spacer to improve the pharmacokinetic properties, solubility, and stability of therapeutic peptides and proteins.
  • Click Chemistry: The azide terminus enables efficient, site-specific conjugation via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions.
  • Surface Modification: Functionalizes nanoparticles, quantum dots, and other material surfaces for targeted drug delivery and diagnostic applications.
  • Hydrogel and Biomaterial Synthesis: Acts as a cross-linking agent in the development of biocompatible hydrogels for tissue engineering and controlled release systems.
  • Diagnostic Reagent Preparation: Utilized in the fabrication of biosensors and immunoassay components by linking recognition elements to signal reporters.
  • Polymer Chemistry: A building block for synthesizing functionalized block copolymers with tailored properties.

Basic Information

Product Name Bocnh-Peg11-Ch2Ch2N3
CAS No. 2395004-21-2
Molecular Formula C34H66N4O14
Molecular Weight 754.91 g/mol
Synonyms Boc-NH-PEG11-azide; tert-Butyl (2-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethyl)carbamate; Azido-PEG11-Boc-amine; Boc-amine-PEG11-N3; Heterobifunctional PEG Linker, Boc-amine/azide; 11-Amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-35-oic acid tert-butylamide azide derivative; PEG-based crosslinker
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Quality Control

Every batch of Bocnh-Peg11-Ch2Ch2N3 is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supplied with comprehensive documentation, including a detailed Certificate of Analysis (COA) available upon request, which confirms compliance with specifications for research and GMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item Specification
Appearance Colorless to pale yellow viscous liquid or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Molecular Weight Confirmation (MS) Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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