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Bocnh-Peg11-Ch2Ch2N3 CAS NO 2395004-21-2
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CAS No.:2395004-21-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Bocnh-Peg11-Ch2Ch2N3 (CAS NO 2395004-21-2) is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring a Boc-protected amine at one terminus and an azide group at the other. This compound is essential for creating stable, water-soluble conjugates in advanced bioconjugation and materials science applications. It is specifically designed for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise and reliable cross-linking agents for drug delivery systems, surface functionalization, and the synthesis of complex biomaterials.
Application
- Bioconjugation and ADC Development: Used as a key linker for attaching cytotoxic drugs to antibodies or proteins in Antibody-Drug Conjugate (ADC) research and production.
- PEGylation: Serves as a functionalized PEG spacer to improve the pharmacokinetic properties, solubility, and stability of therapeutic peptides and proteins.
- Click Chemistry: The azide terminus enables efficient, site-specific conjugation via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions.
- Surface Modification: Functionalizes nanoparticles, quantum dots, and other material surfaces for targeted drug delivery and diagnostic applications.
- Hydrogel and Biomaterial Synthesis: Acts as a cross-linking agent in the development of biocompatible hydrogels for tissue engineering and controlled release systems.
- Diagnostic Reagent Preparation: Utilized in the fabrication of biosensors and immunoassay components by linking recognition elements to signal reporters.
- Polymer Chemistry: A building block for synthesizing functionalized block copolymers with tailored properties.
Basic Information
| Product Name | Bocnh-Peg11-Ch2Ch2N3 |
| CAS No. | 2395004-21-2 |
| Molecular Formula | C34H66N4O14 |
| Molecular Weight | 754.91 g/mol |
| Synonyms | Boc-NH-PEG11-azide; tert-Butyl (2-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethyl)carbamate; Azido-PEG11-Boc-amine; Boc-amine-PEG11-N3; Heterobifunctional PEG Linker, Boc-amine/azide; 11-Amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-35-oic acid tert-butylamide azide derivative; PEG-based crosslinker |
| EINECS | Contact for details |
Quality Control
Every batch of Bocnh-Peg11-Ch2Ch2N3 is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supplied with comprehensive documentation, including a detailed Certificate of Analysis (COA) available upon request, which confirms compliance with specifications for research and GMP-grade applications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow viscous liquid or solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Molecular Weight Confirmation (MS) | Conforms |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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