Description

1,6-Naphthyridine-3-Carboxamide, 4-(4-Cyano-2-Methoxyphenyl)-1,4-Dihydro-2,8-Dimethyl-5-[(1-Methylcyclopropyl)Methoxy]-, (4R)- is a high-purity, chiral organic compound of significant interest in advanced pharmaceutical research and development. This complex molecule serves as a critical pharmacological intermediate or reference standard for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential new drug candidates, particularly in oncology, neurology, or virology research.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in API manufacturing processes.
• Biochemical Research: Employed as a tool compound in high-throughput screening (HTS) and target-based drug discovery programs to study biological pathways.
• Process Chemistry: Serves as a starting material or advanced intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Custom Synthesis: A precursor for the preparation of more complex, proprietary derivatives for specialized client projects.

Basic Information

Product Name	1,6-Naphthyridine-3-Carboxamide, 4-(4-Cyano-2-Methoxyphenyl)-1,4-Dihydro-2,8-Dimethyl-5-[(1-Methylcyclopropyl)Methoxy]-, (4R)-
CAS No.	2389019-64-9
Molecular Formula	C24H26N4O3
Molecular Weight	418.49 g/mol
Synonyms	(4R)-4-(4-Cyano-2-methoxyphenyl)-1,4-dihydro-2,8-dimethyl-5-[(1-methylcyclopropyl)methoxy]-1,6-naphthyridine-3-carboxamide; (4R)-4-(4-Cyano-2-methoxyphenyl)-5-((1-methylcyclopropyl)methoxy)-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide; UNII-8G9J8X2V8U; 8G9J8X2V8U; 1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-1,4-dihydro-2,8-dimethyl-5-[(1-methylcyclopropyl)methoxy]-, (4R)-; (R)-4-(4-Cyano-2-methoxyphenyl)-5-((1-methylcyclopropyl)methoxy)-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridine-3-Carboxamide derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as chiral purity, chemical purity (by HPLC), and residual solvent content. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.