Description

1-Piperazinecarboxylic Acid, 2-(Cyanomethyl)-, 1,1-Dimethylethyl Ester, (2R)- is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with precise biological activity. This intermediate is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry for efficacy.
• Peptidomimetics & Drug Discovery: Serves as a constrained amino acid analog in the design of peptide-like molecules to improve metabolic stability and binding affinity.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 2-(Cyanomethyl)-, 1,1-Dimethylethyl Ester, (2R)-
CAS No.	2387560-41-8
Molecular Formula	C11H19N3O2
Molecular Weight	225.29 g/mol
Synonyms	(2R)-2-(Cyanomethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl (2R)-2-(cyanomethyl)piperazine-1-carboxylate; (R)-2-(Cyanomethyl)piperazine-1-carboxylic acid tert-butyl ester; (R)-N-Boc-2-(cyanomethyl)piperazine; Boc-(R)-2-(Cyanomethyl)piperazine; (R)-Boc-2-Cyanomethylpiperazine; (2R)-2-(Cyanomethyl)piperazine-1-carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarboxylic Acid, 2-(Cyanomethyl)-, 1,1-Dimethylethyl Ester, (2R)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.