Description

Pyrazine, 2-Chloro-5-Iodo-3-Methyl- is a high-value, multi-substituted heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique halogenated structure provides versatile reactivity for constructing complex molecular architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other heterocyclic-based therapeutics.
• Agrochemical Research: Serves as a crucial building block for synthesizing new generations of herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis or as a precursor for functionalized materials.
• Organic Electronic Materials: Potential precursor for the synthesis of nitrogen-containing heterocyclic compounds used in organic light-emitting diodes (OLEDs) or semiconductors.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules or probes for studying biological pathways and target engagement.
• Custom Synthesis and Scale-Up: Supplied for contract research organizations (CROs) and chemical development companies requiring reliable, high-purity advanced intermediates.

Basic Information

Item	Detail
Product Name	Pyrazine, 2-Chloro-5-Iodo-3-Methyl-
CAS No.	2385987-24-4
Molecular Formula	C5H4ClIN2
Molecular Weight	254.45 g/mol
Synonyms	2-Chloro-5-iodo-3-methylpyrazine; 3-Methyl-2-chloro-5-iodopyrazine; 5-Iodo-2-chloro-3-methylpyrazine; 2-Chloro-3-methyl-5-iodopyrazine; Methylchloroiodopyrazine; Pyrazine, chloroiodomethyl-; (Chloro)(iodo)(methyl)pyrazine; CAS 2385987-24-4
EINECS	Contact for details

Quality Control

Every batch of Pyrazine, 2-Chloro-5-Iodo-3-Methyl- is produced and controlled under a strict quality management system. We ensure high purity and batch-to-batch consistency through comprehensive analytical techniques including NMR, HPLC, and GC-MS. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.