Description

m-Peg24-Alcohol is a high-purity, monodisperse polyethylene glycol (PEG) derivative terminated with a primary hydroxyl group. This compound is a critical building block in bioconjugation and pharmaceutical formulation, offering precise control over hydrophilicity, solubility, and molecular spacing. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require a well-defined PEG linker for creating stable, functionalized compounds.

Application

• Pharmaceutical Linker: A key intermediate for attaching drug molecules, proteins, or peptides to enhance solubility, prolong circulation half-life, and reduce immunogenicity.
• Bioconjugation Reagent: Used in the synthesis of antibody-drug conjugates (ADCs), PEGylated proteins, and diagnostic probes.
• Polymer Chemistry: Serves as a macroinitiator or monomer for synthesizing block copolymers with tailored amphiphilic properties.
• Surface Modification: Employed to create hydrophilic, protein-resistant coatings on nanoparticles, medical devices, and diagnostic surfaces.
• Cross-linking Agent: Utilized in hydrogel formation for drug delivery systems and tissue engineering scaffolds.
• Solubility Enhancer: Improves the aqueous solubility of poorly soluble active pharmaceutical ingredients (APIs) in pre-formulation studies.

Basic Information

Product Name	m-Peg24-Alcohol
CAS No.	2376450-73-4
Molecular Formula	C49H100O25
Molecular Weight	~1089.3 g/mol
Synonyms	mPEG24-OH; Monomethoxy Polyethylene Glycol 24 Alcohol; α-Methyl-ω-hydroxypoly(oxy-1,2-ethanediyl); 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-Tetracosaoxaheptatetracontan-73-ol; Methoxy-PEG24-alcohol; PEG 1000 Monomethyl Ether (approx.); Poly(ethylene glycol) methyl ether (Mn ~1000); m-PEG 1000
EINECS	Contact for details

Quality Control

Every batch of m-Peg24-Alcohol is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a full Certificate of Analysis (COA) detailing key parameters such as assay, polydispersity index (PDI), and residual solvents, meeting the stringent requirements for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Polydispersity Index (PDI)	≤ 1.05
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.