Description

1-Piperazinecarboxylic Acid, 4-[6,8-Dichloro-2-(Methylthio)Pyrido[3,4-D]Pyrimidin-4-Yl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring reliable, high-quality building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Serves as a critical precursor in the multi-step synthesis of complex APIs.
• Biochemical Research: Potential tool compound for studying specific enzymatic pathways and biological mechanisms.
• Contract Manufacturing (CMO/CDMO): Supplied to organizations specializing in the custom synthesis of complex molecules for clinical trials.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-[6,8-Dichloro-2-(Methylthio)Pyrido[3,4-D]Pyrimidin-4-Yl]-, 1,1-Dimethylethyl Ester
CAS No.	2368910-58-9
Molecular Formula	C18H21Cl2N5O2S
Molecular Weight	438.36 g/mol
Synonyms	tert-Butyl 4-(6,8-dichloro-2-(methylthio)pyrido[3,4-d]pyrimidin-4-yl)piperazine-1-carboxylate; 4-[6,8-Dichloro-2-(methylsulfanyl)pyrido[3,4-d]pyrimidin-4-yl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 6,8-Dichloro-2-(methylthio)-4-(4-Boc-piperazin-1-yl)pyrido[3,4-d]pyrimidine; Boc-Protected Dichloro Methylthio Pyridopyrimidine Piperazine Derivative
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 4-[6,8-Dichloro-2-(Methylthio)Pyrido[3,4-D]Pyrimidin-4-Yl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.