Description

Diketone-Peg11-Diketone CAS NO 2353409-87-5 is a specialized polyethylene glycol (PEG)-based diketone derivative, designed as a high-purity functional linker and spacer molecule. Its precise chemical structure provides controlled hydrophilicity and reactivity, making it a critical component for advanced material synthesis and bioconjugation. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, custom-length PEG spacers for developing novel therapeutics, diagnostics, and functional polymers.

Application

• As a heterobifunctional crosslinker for the site-specific conjugation of proteins, peptides, or antibodies with small molecule drugs, dyes, or solid surfaces.
• As a hydrophilic spacer arm in the synthesis of prodrugs, antibody-drug conjugates (ADCs), and targeted therapeutic agents to improve solubility and pharmacokinetics.
• As a key intermediate in the preparation of functionalized hydrogels, smart polymers, and biocompatible coatings for medical devices.
• In the development of diagnostic assays and biosensors, where its PEG chain reduces non-specific binding and improves signal-to-noise ratios.
• For modifying nanoparticle surfaces (e.g., liposomes, dendrimers, inorganic NPs) to enhance colloidal stability, biocompatibility, and targeting capabilities.
• As a building block in materials science for creating non-fouling surfaces and controlled-release matrices.

Basic Information

Product Name	Diketone-Peg11-Diketone
CAS No.	2353409-87-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,3-Diketone-PEG11-1,3-Diketone; Bis(1,3-diketone)-PEG11; α,ω-Bis(acetylacetone)-undecaethylene glycol; PEG11 Diketone Dimer; 11-Unit PEG Diketone Linker; Heterobifunctional PEG11 Diketone; AcAc-PEG11-AcAc (AcAc = acetylacetone); Poly(ethylene glycol) bis(1,3-diketone) (n=11)
EINECS	Contact for details

Quality Control

Our Diketone-Peg11-Diketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and commercial applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Average Molecular Weight	Within ± 2% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.