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Octanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-5-Propyl-, (2S)- CAS NO 2350457-47-3
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CAS No.:2350457-47-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Octanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-5-Propyl-, (2S)- is a high-purity, non-natural amino acid derivative featuring a fluorenylmethyloxycarbonyl (Fmoc) protecting group on the amine functionality. This compound is specifically engineered for use in solid-phase peptide synthesis (SPPS), where it serves as a critical building block for introducing modified amino acid residues into complex peptide sequences. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require precise control over peptide structure and properties. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for your most demanding applications.
Application
- Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of custom peptides and peptidomimetics.
- Pharmaceutical Research & Development: Used in the discovery and development of novel therapeutic peptides, including hormone analogs, antimicrobial peptides, and targeted drug conjugates.
- Bioconjugation and Probe Development: Facilitates the site-specific incorporation of functional handles or labels into peptides for diagnostic, imaging, or targeting applications.
- Material Science: Serves as a monomer for creating bio-inspired polymers and peptide-based nanomaterials with tailored self-assembly properties.
- Academic Research: A vital reagent for studying protein-protein interactions, enzyme specificity, and structure-activity relationships (SAR) in biochemical laboratories.
Basic Information
| Product Name | Octanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-5-Propyl-, (2S)- |
| CAS No. | 2350457-47-3 |
| Molecular Formula | C26H31NO4 |
| Molecular Weight | 421.53 g/mol |
| Synonyms | Fmoc-(S)-2-Amino-5-propyloctanoic acid; Fmoc-5-Propyl-D,L-norleucine (check stereochemistry); (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-5-propyloctanoic acid; N-α-Fmoc-5-propylnorleucine; Fmoc-5-propyl-Nle-OH; Protected amino acid CAS 2350457-47-3; Fmoc-D,L-α-amino-5-propyloctanoic acid; N-Fmoc-2-amino-5-propyloctanoic acid |
| EINECS | Contact for details |
Quality Control
Our Octanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-5-Propyl-, (2S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to ensure it meets the stringent requirements for pharmaceutical research and peptide synthesis.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% (S-isomer) |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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