Description

m-Peg17-Acid is a high-purity, monodisperse polyethylene glycol (PEG) derivative featuring a carboxylic acid functional group at one terminus. This bifunctional molecule is engineered to serve as a critical linker and modifier in advanced bioconjugation and pharmaceutical formulation, enabling precise control over solubility, pharmacokinetics, and molecular assembly. It is essential for R&D and production teams in the pharmaceutical, biotech, and advanced materials sectors seeking to enhance drug delivery systems, create functionalized surfaces, and develop novel polymer conjugates.

Application

• Bioconjugation & Drug Delivery: A key linker for attaching therapeutic agents (e.g., peptides, proteins, small molecules) to carriers like nanoparticles or antibodies to improve solubility, stability, and circulation time.
• PEGylation Reagent: Used to modify proteins and peptides, reducing immunogenicity and proteolytic degradation while enhancing in vivo half-life.
• Polymer & Material Science: Serves as a macro-initiator or building block for synthesizing functionalized block copolymers, hydrogels, and surface coatings.
• Diagnostic Reagents: Functionalization of probes, dyes, and imaging agents for diagnostic assays and biomedical research.
• Crosslinking Agent: Utilized in the preparation of biodegradable matrices and scaffolds for tissue engineering applications.
• Surface Modification: Imparts hydrophilicity and bio-inert properties to surfaces of medical devices and implants.

Basic Information

Product Name	m-Peg17-Acid
CAS No.	2346581-96-0
Molecular Formula	C37H74O19
Molecular Weight	822.96 g/mol
Synonyms	17-Methoxy-3,6,9,12,15-pentaoxaheptacosanoic Acid; α-Methoxy-ω-carboxy heptadeca(ethylene glycol); mPEG17-Acid; Monomethoxy PEG17 Carboxylic Acid; mPEG17-COOH; PEG Methyl Ether Carboxylic Acid (MW ~823); 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-Methoxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic Acid
EINECS	Contact for details

Quality Control

Our m-Peg17-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity, precise molecular weight, and functional group integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Molecular Weight (MS)	820 - 826 g/mol
Acid Value (Titration)	67 - 71 mg KOH/g
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.